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Avoid GHK-Cu if you have Wilsons disease (due to the risk of copper accumulation), an active or history of certain cancers (due to growth factor effects and angiogenesis promotion), are pregnant or breastfeeding (safety not definitively established), or have known copper metabolism disorders or peptide allergies

Auerhalb der Norm (roter Bereich): eine klinisch relevante Unterversorgung

doi: 10.1016/j.tice.2025.103305 92 ZhangCZhuWMengQLianNWuJLiuBet al

By contrast, peptides such as PYY and apelin were discontinued primarily due to formulation limitations or tolerability at supraphysiologic dosespharmacologic rather than biological failuresand therefore meet criteria for re-evaluation